Harnessing haemoproteins

Reactions of Haematins and Haemoproteins

1. It is shown that free haematins will react with nitric oxide under certain conditions giving compounds with characteristic absorption spectra. 2. The reactions of nitric oxide with both protohaematin and urohaematin were examined. In acid solution each of these haematins changes colour from reddish brown to a bright red in the presence of nitric oxide, and two strong absorption bands appear ...

The cytochrome P450 IV family: constitutive and inducible haemoproteins.

Mammalian cytochrome 1'-450 exists as a multigene family expressing a spectrum of structurally and functionally distinct isoenzymes involved in the biotransformation of both exogenous and endogenous substrates [ l , 21. Although a generally accepted isoenzyme nomenclature based on divergent evolution and nucleotide/amino acid homologies is now widely used [I], i t is still useful, under certain...

Use of carbon monoxide for detecting denaturation in haemoproteins.

Harnessing ontologies

Engineered nanomaterials (ENMs) are being developed to meet specific application needs in diverse domains across the engineering and biomedical sciences (e.g. drug delivery). However, accompanying the exciting proliferation of novel nanomaterials is a challenging race to understand and predict their possibly detrimental effects on human health and the environment. The eNanoMapper project (www.e...

Harnessing Complexity in Design

Large scale design problems involve complex systems. The complexity arises from the nature of the large interconnected systems and is escalated by the background, personal characteristics, and perspectives of the individuals working on the design team. It is important for designers to understand complexity and how complexity affects the understanding and prediction of system behavior. It is eve...